Course descriptions

Advanced topics in pharmacoepidemiology   

Professor Alan Brookhart, BA, MAMS, MA, PhD
Leah McGrath, BS, MHS, PhD

Over the course of two days, we will review fundamental analytic methods in pharmacoepidemiology, including estimating of causal effects using a new user study design combined with propensity score methods. The remainder of this course will focus on extending this basic study paradigm to estimate cumulative risk functions in settings with competing risks, selection bias, dependent censoring, and multiple treatment groups. We will illustrate how this expanded set of tools permits one to answer a wide range of additional questions, such as estimating the effect of medication adherence and time-dependent treatment protocols. We will also demonstrate how the results from such analyses can be depicted using compelling data visualizations. Students will conduct their own analysis using R/Shiny tools developed by the instructor.

Monday-Tuesday, 12-13 June 2017

Missing data issues  

Prof. Irene Petersen, MSc, PGCert, P. Grad Dip, PhD

After a discussion of missing data mechanisms, the course will review ad-hoc methods of dealing with missing data and focus on theory, practice and reporting of studies using multiple imputation.

Wednesday, 14 June 2017

Self-controlled designs   

Associate professor Ian Douglas, BSc, MSc, PhD 

Amongst many ways to account for confounding in observational studies, self-controlled methods have been gaining popularity over recent years. Designs such as the self-controlled case series and the case cross-over make comparisons within individuals, and remove the need to account for between person differences. We will explore these methods, their underlying assumptions, and some examples of their application.

Thursday, 15 June 2017

Perinatal and reproductive pharmacoepidemiology

Prof. Irene Petersen, MSc, PGCert, P. Grad Dip, PhD
Prof. Vera Ehrenstein, MPH, DSc

This special-topics session will address issues in pharmacoepidemiology as applied to drug use in pregnancy and other reproductive issues.

Friday, 16 June 2017 (half day)